Major Depressive Disorder. Depressive episode
Conditions
Interventions
Intervention 1: Capsule aripiprazole15-30 mg/day as intervention group for 12 weeks. Intervention 2: citalopram 20-40 mg/day as control group for 12 weeks.
Treatment - Drugs
Capsule aripiprazole15-30 mg/day as intervention group for 12 weeks
citalopram 20-40 mg/day as control group for 12 weeks
Sponsors
Vice chancellor for research, Kurdistan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of Major Depressive Disorder based on DSM-IV criteria; presence of mixed depression criteria (psychomotor or inner agitation). Exclusion criteria: Presence of Psychosis; any diagnosis in Axis I and II; Receiving psychotropic medications; receiving any antidepressants during past one month or ECT during past two months; neurological disease; nursing and pregnant women; substance abuse during past two weeks
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: Baseline and weeks 2-4-6-12 after beginnig of treatment. Method of measurement: by Hamiltion Depression Rating Scale 17-Item. | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of anxiety. Timepoint: Baseline and weeks 2,4, 6 and 12 after starting treatment. Method of measurement: by Hamilton rating scale for anxiety.;Severity of agitation. Timepoint: Baseline and weeks 2,4, 6 and 12 after starting treatment. Method of measurement: by Young mania rating scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Farzin Rezaei
Kurdistan University of Medical Sciences
Outcome results
None listed