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Beneficial effects of helicobacter pylori eradication on severity and frequency of migrane headache

Beneficial effects of helicobacter pylori eradication on severity and frequency of migrane headache

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201202018896N1
Enrollment
80
Registered
2012-05-02
Start date
2012-01-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migrane. Migraine without aura [common migraine]

Interventions

Standard four-drug protocol for H. pylori eradication was employed with Omeprazol 20 mg Bid, Bismuth 240 mg Bid, Tetracyclin 500 mg Qid, and Metronidazol 500 mg Bid for four weeks..
Treatment - Drugs
Standard four-drug protocol for H. pylori eradication was employed with Omeprazol 20 mg Bid, Bismuth 240 mg Bid, Tetracyclin 500 mg Qid, and Metronidazol 500 mg Bid for four weeks.

Sponsors

Vice-chancellor for research of Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All people with headaches meet the International Headache Society criteria (moderate to severe headache, unilateral, pulsatile; intensified with routine activities with nausea and vomiting associated with photophobia and multiple attacks during 72-4 h). Exclusion criteria: lack of patient satisfaction; identify other causes of headache during treatment and previous treatment of Helicobacter pylori

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The number of migraine attacks. Timepoint: Before and after the standard treatment for H. pylori infection. Method of measurement: the average monthly number of headache attacks (based on number of attacks per month.;Severity of migraine attacks. Timepoint: Before and after the standard treatment for H. pylori infection. Method of measurement: The severity of headache attacks (on the basis of numbers 10_1).

Secondary

MeasureTime frame
Eradication rate of Helicobacter pylori infection [Helicobacter pylori infection in patients with migraine. Timepoint: After treatment. Method of measurement: Urea breath test to confirm eradication.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloufar Hhemmati

Hamedan University of Medical Sciences

shakhenabat1979@yahoo.com+98 81 1838 0703

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026