Preterm labor. Preterm labour without delivery
Conditions
Interventions
Intervention 1: First group (A) will be giving 4 gram Magnesium Sulfate as a loading dose then countining 2 gram every hour until 48 hours(positive Patella reflex ,at least 12 times respiratory rates
Treatment - Drugs
First group (A) will be giving 4 gram Magnesium Sulfate as a loading dose then countining 2 gram every hour until 48 hours(positive Patella reflex ,at least 12 times respiratory rates,urine output at
The other group will be giving Nifedipine tablet(20mg) after half an hour will be given other 20 mg of Nifedipine tablet,if contractions persist ,giving 20 mg Nifedipin will be countining every 3-8
Sponsors
Tabriz University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
14 Years to 45 Years
Inclusion criteria
Inclusion criteria: Criteria include more than 6 contractions per hour resulting in a demonstrated cervical change or presumed prior cervical change (transvaginal cervical length 50% cervical effacement, or cervical dilation =2 cm) ;Gestational ages are between 26-34 ; Bloody show ; Nully fetus pregnant ; Intact membranes ; BP>90 mmhg in Nifedipine group exclude criteria Oligohydramnios and polyhydramnios ;Nonreactive nonstress test results ;Positive contraction stress test results ; Absent or reversed diastolic flow upon Doppler examination of umbilical blood flow ; Repetitive severe variable decelerations ;Significant vaginal bleeding consistent with abruption and placenta previa ; PPROM ;Multi fetus pregnancy ;BP<90 mmhg in Nifedipine group ; Intrauterine infection ; Pyelonefrites ;Preeclampse and GTM and anomalies
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effecement. Timepoint: In addmission. Method of measurement: Vaginal examination.;Dillatation. Timepoint: In admmision. Method of measurement: Vaginal examination.;Length and diuration of contractions. Timepoint: Every 10 minute. Method of measurement: Abdominal tough of uterus. | — |
Secondary
| Measure | Time frame |
|---|---|
| Feeling of fetal movment by mother. Timepoint: In an hour. Method of measurement: Abdominal touching.;Unreliable paterns of fetal heart rate. Timepoint: In 20 minnutes. Method of measurement: Record by monitoring devices.;Newborn Apgar. Timepoint: In first and fifth min. Method of measurement: Apgars score.;ABG of umblical cord blood. Timepoint: After birth. Method of measurement: ABG devices.;Meconium. Timepoint: After birth. Method of measurement: Finding meconium on neuborn skin or amniotic fluid or amblical cord. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFereshteh Fartash
Nursing and Midwifery University of Tabriz
Outcome results
None listed