Haloperidol midazolam versus ketamine midazolam in agitated patients

Comparison of the efficacy of haloperidol combination with midazolam versus haloperidol ketamine in patients with agitation in emergency room

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120130008872N13

Enrollment

Registered

2019-10-23

Start date

2019-11-20

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

agitation.

Interventions

Intervention 1: Intervention group: A Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention haloperidol. Intervention 2: Control group: B will receive 2.5 mg haloperidol iv and

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All agitated patients above 18 years old and admitted to emergency ward

Exclusion criteria

Exclusion criteria: Pregnant women age<18 y sever head trauma suspected ICP rising seizure history unwilling to participation in the study hypoglycemia hypoxemia all conditions that have treatable medical condition as a reason for agitation

Design outcomes

Primary

Measure	Time frame
Agitation level. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: altered mental scale score(AMSS).	—

Secondary

Measure	Time frame
Spo2. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: pulsoxymerer.;Respiratory Rate. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: numbers per min.;Blood pressure. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: mmhg.	—

Measure

Time frame

Spo2. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: pulsoxymerer.;Respiratory Rate. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: numbers per min.;Blood pressure. Timepoint: Before intervention and 5, 15, 30, 90, 120 min and 4 hours after intervention. Method of measurement: mmhg.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Saeedi

Tehran University of Medical Sciences

m_saeedi@tums.ac.ir+98 21 8490 2719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026