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Effects of erythropoietin in palatal wound healing, Effect of Erythropoietin on healing of gingival graft

The Eeffect of Topical Erythropoietin on Palatal Wound Healing Subsequent to Free Gingival Graft in patients with insufficient keratinized gingiva. Evaluation of Topical Erythropoietin Application on the Healing Outcome of Gingival Graft Recipient Site; A Randomized Controlled Clinical Trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201278830N1
Enrollment
24
Registered
2016-10-22
Start date
2016-10-22
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

palatal wound.

Interventions

Intervention 1: Control group:A 10*15 mm template is used to harvest a graft from premolar and first molar area of the hard palate and is fixed in the recipient site.In control site: After bleeding co
SUPABON, SUPA, Iran). Then the wound sites are covered with a foil and the periodontal pack (coe pak, GC America Co., USA). Intervention 2: Intervention group: A 10*15 mm template is used to harvest

Sponsors

Research Affairs, Tehran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: age of 18 years old or above periodontal health; need for gingival graft in order to augment keratinized gingiva in at least two mandibular areas

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Epithelialization. Timepoint: on days 7, 14 , 21 and 28. Method of measurement: Hydrogen Peroxide 3% application.;Degree of healing. Timepoint: on days 7, 14,21,28, 60, 90. Method of measurement: Graft color match, contour, and texture.;Inflammation on recipient site. Timepoint: on days 7, 14,21,28, 60, 90. Method of measurement: based on the size of the red inflammatory halo around the graft.

Secondary

MeasureTime frame
Inflammation. Timepoint: on days 7,14,21 and 28. Method of measurement: direct observation of the region, also photographs taken from test and control areas are prepared to be observed by three periodontists.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiamak Yaghobee

Tehran University of Medical Sciences

ninarouzmeh@yahoo.com+98 21 8835 1168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 20, 2026