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The effect of cyproheptadine on pediatric growth

The effect of cyproheptadin hydrochloride in treatment of mild to moderate failure to thrive in children who referred to clinics of Shiraz University of Medical Sciences at 1390

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201268827N1
Enrollment
80
Registered
2012-02-22
Start date
2011-11-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Failure to thrive. Other lack of expected normal physiological development

Interventions

Intervention 1: Cyproheptadine 0.25 mg/kg/day (twice daily) for 1 month. Intervention 2: Multivitamine, 0.25 mg/kg/d(twice daily) for 1 month.
Treatment - Drugs
Placebo
Cyproheptadine 0.25 mg/kg/day (twice daily) for 1 month
Multivitamine, 0.25 mg/kg/d(twice daily) for 1 month

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 5 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children aged between2 to 5 years old and have mild to moderate failure to thrive. Exclusion criterion: Having organic causes or acute or chronic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Weight. Timepoint: At begining of study, 1 month after begining and 1 month after termination of study. Method of measurement: Kilogram.;Height. Timepoint: At begining of study, 1 month after begining and 1 month after termination of study. Method of measurement: Cm.

Secondary

MeasureTime frame
Drowsiness. Timepoint: During drug consumption. Method of measurement: History and Physical examination.;Restlessness. Timepoint: During drug consumption. Method of measurement: History and Physical Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhadijeh Sadat Najib

Shiraz University of Medical Sciences

nzahrasan@yahoo.com+98 71 1647 4298

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026