Evaluate the effect of probiotics and phase 1 of periodontal treatment on patient with moderate to severe periodontitis

Comparative study of clinical and microbial effect of probiotics and phase 1 of periodontal treatment on patient with moderate to severe periodontitis in Tehran university in 1390

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201201258825N1

Enrollment

Registered

2012-08-20

Start date

2012-08-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Scaling and root planning and ? probiotic mouth wash in case group. Intervention 2: Scaling and root planning and placebo mouthwash in control group.

Treatment - Drugs

Scaling and root planning and ? probiotic mouth wash in case group

Scaling and root planning and placebo mouthwash in control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: moderate to severe periodontitis and the presence of pockets more than 4mm. Patients must have the following parameters: 1.PPD>= 4mm; 2.CAL>=3mm and 3.bone loss >=3mm. Exclusion criterion: 1.taking antibiotic over 3months ago; 2.immune deficiency disorders; 3.lactose intolerance and 4.taking immune suppressor drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Gingival index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Plaque index. Timepoint: Day 0,14 and 28. Method of measurement: Plaque staining.;Periodontal pocket depth. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Colony of Aggrebacter actinomycetcomitans. Timepoint: Day 0,14 and 28. Method of measurement: Colony count.;Bleeding on probing. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Periodontal disease index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.	—

Measure

Time frame

Gingival index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Plaque index. Timepoint: Day 0,14 and 28. Method of measurement: Plaque staining.;Periodontal pocket depth. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Colony of Aggrebacter actinomycetcomitans. Timepoint: Day 0,14 and 28. Method of measurement: Colony count.;Bleeding on probing. Timepoint: Day 0,14 and 28. Method of measurement: Prob.;Periodontal disease index. Timepoint: Day 0,14 and 28. Method of measurement: Prob.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Neda sajedi nejad

Tehran university of medical science

neda_sajedi@yahoo.com+98 21 2213 7768

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026