premenstural syndrom. Premenstrual tension syndrome
Conditions
Interventions
Intervention 1: chamomile extract, 100 mg capsule oral? 21st day till the beginning of next cycle one capsule three times daily. Intervention 2: Mefenamic Acid capsules, 250 mg capsule oral , 21st da
Treatment - Drugs
chamomile extract, 100 mg capsule oral? 21st day till the beginning of next cycle one capsule three times daily
Mefenamic Acid capsules, 250 mg capsule oral , 21st day till the beginning of next cycle one capsule three times daily
Sponsors
The international Branch of Shahid Beheshti University of Medical Siences and Health Services
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Single students; 18-35 years old; With normal body mass index (19.8 -26) ; No smoking; Regular menstrual cycles( 21-35 days) ; No physical disease (digestive problems like ulcers, diabetes, seizure disorders, hypothyroidism and endometriosis, and ...)and no known mental illnes; At least 5 symptoms of premenstrual syndrome symptoms in a temporary form of DSMIV with necessarily one symptoms from first to fourth (1 - Markedly depressed, mood and feelings of hopelessness, 2 - Significant anxiety, tension, feelings of impatience and anxiety, 3- Significant mood instability, such as sudden sadness, 4 - Continuous and apparent anger or irritability or increased interpersonal conflicts); lack of depression based on the Beck Depression questionnaire ; no history of consumption of Certain drugs (hormones, vitamins, antidepressants, herbal medicines, aspirin, warfarin); No allergy to herbal medicines; no sad event such as death of close relatives and surgery in the past six months; Not being professional athlete. Exclusion criteria: Sensitivity to drugs; Incorrect use of capsules (two capsules daily, if not, the person is excluded); Married during the study; Having specific disease and to take medications during the study; Occurrence of a sad event such as death of close relatives and surgery; To exercise professionally.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity of physical symptoms of premenstrual syndrome. Timepoint: pre intervention, first month after intervention, second month after intervention. Method of measurement: Daily form of severity of premenstrual syndrome.;The severity of psychological symptoms of premenstrual syndrome. Timepoint: pre intervention, first month after intervention, second month after intervention. Method of measurement: Daily form of severity of premenstrual syndrome.;The severity of symptoms of premenstrual syndrome. Timepoint: pre intervention, first month after intervention, second month after intervention. Method of measurement: Daily form of severity of premenstrual syndrome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of chamomile. Timepoint: first month after intervention, second month after intervention. Method of measurement: Questionnaire of effects and side effects of medication.;Side effects of mefanamic acid capsule. Timepoint: first month after intervention, second month after intervention. Method of measurement: Questionnaire of effects and side effects of medication. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarangis Sharifi
The international Branch of Shahid Beheshti University Of Medical Siences and Health Services
Outcome results
None listed