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Therapeutic effects of oral zinc supplementation in acute watery diarrhea of children

Therapeutic effects of oral zinc supplementation in acute watery diarrhea of children with moderate dehydration: a double blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201241580N2
Enrollment
320
Registered
2012-02-17
Start date
2008-04-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Watery Diarrhea. Gastroenteritis and colitis of unspecified origin

Interventions

Intervention 1: Zinc Sulfate Syrup, 1mg/kg/day/BID. Intervention 2: Placebo with similar taste, color and smell was applied with similar option (1 ml/kg/day) for control group.
Treatment - Drugs
Placebo
Zinc Sulfate Syrup, 1mg/kg/day/BID
Placebo with similar taste, color and smell was applied with similar option (1 ml/kg/day) for control group.

Sponsors

Vice Chencellor for Research, Urmia Univesity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 5 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all 9 months to 5 years old children who were admitted with acute watery diarrhea and moderate dehydration at Children Ward of Motahari Hospital, Urmia, Iran in 2008 were recruited. The exclusion criteria were diagnosed chronic disease (Cystic fibrosis, inflammatory bowel diseases, malabsorption); severe malnutrition (weight curve's was under percentage 3% for age); dysentery and bloody diarrhea confirmed with existence of red blood cell (RBC) or white blood cell (WBC) in stool examination (S/E); recent consumption of antibiotics; severe dehydration or persistent vomiting; recent consumption of zinc supplements (last month) and drug intolerance.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Admission period. Timepoint: days of admission. Method of measurement: days recorded in dossier.

Primary

MeasureTime frame
Stop Diarrhea. Timepoint: daily. Method of measurement: study of records & asking from mother.;Stool consistency. Timepoint: daily. Method of measurement: Mothers report.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahsanam Gheibi

Urmia University of medical Sciences

drgheibi@yahoo.com+98 44 1222 6969

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026