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The effect of plasma rich growth factor in treatment of molar class II furcation involvement

The effect of plasma rich growth factor in treatment of molar class II furcation involvement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201231760N15
Enrollment
12
Registered
2012-02-22
Start date
2012-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

molar class II furcation involvment. Chronic periodontitis

Interventions

Intervention 1: Control group: in one site treatment with double layer of membrane alone the treatment interference with drug. Intervention 2: Intervention group: Treatment with PRGF gel like in furca
Treatment - Drugs
Control group: in one site treatment with double layer of membrane alone the treatment interference with drug
Intervention group: Treatment with PRGF gel like in furcation area that is covered with double layer membrane of biogide.The preparation of PRGF gel: PRGF that 500 microliter in every tube is rich o

Sponsors

Vice Chancellor for Research and Technology, Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who have moderate to severe periodontitis that have class II furcation involvement in buccal or lingual first molar or second molar in mandible; good cooperation after the primary periodontal treatment; The horizontally amount to enter the probe is >3mm. Exclusion criteria: the patients who have systemic disease; the patients who need the prophylactic treatment of antibiotic for prevention of bacterial endocarditis; Smoker patient; the teeth that have anatomical complication like cervical enamel projection, bi furcation ridge concavity, accessory canal and mobility >class II; The patient who uses the drugs that interact with periodontal healing, prescience of caries and filling in furcation area and presence of contra indication for periodontal surgery; the teeth in clinical view or radiography has evidence of preapical pathology; and regarding to the test performance the patient before surgery if the bleeding time and CBC is abnormal.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Treatment of molar class II furcation involvement. Timepoint: Six months after the start of the intervention. Method of measurement: Clinical examination.

Secondary

MeasureTime frame
Vertical probing depth(VPD). Timepoint: Baseline and immediately before surgery and 1 month after surgery around each tooth. Method of measurement: Clinical examination.;Vertical clinical att level(VCAL). Timepoint: Baseline and immediately before surgery and 1 month after surgery around each tooth. Method of measurement: Clinical examination.;Fonix to base of defect(FBD). Timepoint: During the first surgery and 6 months after surgery to reentry around each tooth. Method of measurement: Clinical examination.;Fonix to Alveolar crest( FAC). Timepoint: During the first surgery and 6 months after surgery to reentry around each tooth. Method of measurement: Clinical examination.;Furcation vertical compoment (FVC). Timepoint: During the first surgery and 6 months after surgery to reentry around each tooth. Method of measurement: Clinical examination.;Furcation horizontal component(FHC). Timepoint: During the first surgery and 6 months after surgery to reentry around each tooth. Method of measurement: Clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHodis Ehsani

Dental School, Babol

Hodis_Ehsani@yahoo.com+98 11 1229 1408

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026