type 2 diabetese melitus. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria : Non-insulin dependent diabetic patients with type 2 diabetes that is diagnosed by a physician, Endocrinologist ; Diabetes duration of at least 2 year ; 20-60 ages ; Hb A1c :6-8% ; Lack of antioxidant supplements such as selenium, zinc, beta carotene, and ... At least 3 months before the study ; not smoking and alcohol ; a willingness to cooperate with exclusion criteria : Patient unwillingness to continue with the plan ; changes in type or dose of medication ; Changes in diet or physical activity every day ; taking any antioxidant supplements ; taking less than 80% of supplements given to patients at baseline (the compaliance lower than %80) ; Recent receive insulin ; pregnancy and lactation ; renal , hepatic , thyroid diseases and anemia ; hypersensitivity to the drug
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: before & after intervention (3 months later). Method of measurement: glucose oxidase method.;Hb A1C. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry.;Insulin. Timepoint: before & after intervention (3 months later). Method of measurement: IRMA.;Insulin resistance. Timepoint: before & after intervention (3 months later). Method of measurement: insulin × glucose / 22.5.;Apo A. Timepoint: before & after intervention (3 months later). Method of measurement: immunotorbidometry.;Apo B. Timepoint: before & after intervention (3 months later). Method of measurement: immunotorbidometry.;Apo B/Apo A-I. Timepoint: before & after intervention (3 months later). Method of measurement: ratio.;High-sensitivity C-Reactive Protein. Timepoint: before & after intervention (3 months later). Method of measurement: ELISA kitt.;Total antioxidant capacity. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry (FRAP).;Malondealdehyde. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry.;Paraoxonase. Timepoint: before & after intervention (3 months later). Method of measurement: colorimetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| -. Timepoint: -. Method of measurement: -. | — |
Countries
Iran (Islamic Republic of)
Contacts
School of Public Health of Tehran University of Medical Sciences