insulinoma. Pancreas, unspecified
Conditions
Interventions
Intervention 1: After localizing the site of the tumor by EUS, fine needle aspiration of the tumor will be performed for cytological evaluation. At least three passes of FNA with a 22-guage needle (C
Treatment - Drugs
Treatment - Surgery
After localizing the site of the tumor by EUS, fine needle aspiration of the tumor will be performed for cytological evaluation. At least three passes of FNA with a 22-guage needle (COOK) will be tak
Control group: the patients with insulinoma treating by surgery
Sponsors
Research Deputy of Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: •Biochemically proven solitary insulinoma •Ages between 18 and 80 years old Exclusion criteria: •Insulinoma size of 2 cm or more •Presence of lymph node, or vascular involvement of the tumor in EUS or spiral CT scan •Presence of liver or other distant metastases in the spiral CT scan •Presence of MEN-1 syndrome •Presence of multiple insulinomas •Inability to localize the tumor by EUS •Unwilling to assign inform consent
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effectivenrss of the process. Timepoint: In the first and third month after treatment, BS level, and also in the third month the size of tumor would be measured and regiter by (EUS) method. Method of measurement: According to check list.;Serum amylase. Timepoint: 12, 24 and48 hours post(EUS). Method of measurement: Patients blood sampling.;Serum lipase. Timepoint: 12, 24 and 48 hours post(EUS). Method of measurement: Patient's blood sampling.;The procedure's time. Timepoint: During sonography and alcohol injection. Method of measurement: According to endoscopist's report. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications. Timepoint: During first 48 hours of admission. Method of measurement: According to physical exams and tests.;Admission time. Timepoint: The average of the patient's spending days while the procedure untill discharging from the hospital. Method of measurement: According to the file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda rabiei
Firoozgar hospital
Outcome results
None listed