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The effect of olfactory stimulation on apnea in premature infants

The effect of olfactory stimulation by vanillin on apnea prevention in premature infants admitted in the hospitals associated to shiraz university of medical sciences,2011

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201078643N1
Enrollment
36
Registered
2012-02-25
Start date
2011-07-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apnea. Other diseases of the respiratory system

Interventions

Intervention 1: Intervention group: On the first two days of the study a 0.04 grams of 2%-saturated vanillin solution is used every 12 hours and on the following three days, no vanillin solution is us
Prevention
Intervention group: On the first two days of the study a 0.04 grams of 2%-saturated vanillin solution is used every 12 hours and on the following three days, no vanillin solution is used with no inter
Control group: newborns are likewise under continuous monitoring but with no interventions.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria: Gestational age<36 weeks; Postnatal age: 2 day old; Birth weigth<2500gr; No need for ventilator; Absence of congenital heart disease. The exclusion criteria: Hypocalcemia; Hypoglycemia;Hb<10; Need for ventilator; Intraventricular hemorrhage during intervention.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Frequency of apnea. Timepoint: 2-7 days of postnatal age. Method of measurement: Pulsoximetry.;Heart rate. Timepoint: 2-7 days of postnatal age. Method of measurement: Pulsoximetry.;Oxygen saturation. Timepoint: 2-7 days of postnatal age. Method of measurement: Pulsoximetry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMrs Mitra Edraki

Shiraz University of Medical Sciences, Fatemeh (P.B.U.H) School of Nursing & Midwifery

Mitraedraki@yahoo.com+98 71 1647 4257

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026