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Effect of preemptive novafen on pain relief after impacted tooth surgery

Survey of effect of preemptive combination of acetaminophen, ibuprofen and caffeine (novafen) on pain relief and analgesic use after surgery of impacted mandible third molars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201078639N1
Enrollment
108
Registered
2014-01-10
Start date
2011-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted teeth. an impacted tooth is a tooth that has failed to erupt because of obstruction by another tooth

Interventions

Intervention 1: 2 Hours Before Surgery, intervention group were given a single dose of the oral combination drug brand Novafen that it is made in Alhavi factory(Acetaminophen (600 mg) + Ibuprofen (4
Treatment - Drugs
2 Hours Before Surgery, intervention group were given a single dose of the oral combination drug brand Novafen that it is made in Alhavi factory(Acetaminophen (600 mg) + Ibuprofen (400 mg) + caffei
2 Hours Before Surgery, control group were given a single dose of the oral Vitamin C (250 mg) that it is made in Darou Pakhsh factory.

Sponsors

Vice Chancellor for Research,Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with impacted mandible third molar need surgery without pain, have a healthy body and able to take medications orally. Exclusion criteria: presence of pain, the use of any pain killer before surgery, having certain medical conditions such as Contraindications for anesthesia, drug allergy, heart disease, thyroid toxicity, immune problems, hypertension, diabetes mellitus and renal and hepatic disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Analgesics. Timepoint: 2,4,6and 8 h after the operation. Method of measurement: Based on the number.;PAIN. Timepoint: 2,4,6and 8 h after the operation. Method of measurement: using a 10-point visual analog scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosein Kimiaei Asadi

Hamadan University of Medical Sciences

kimiaei@umsha.ac.irhkimiaeimd@yahoo.com+98 81 1264 0062

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026