polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: control group: placebo every 20 days for 60 days. Intervention 2: intervantion group: 50000 IU vitaminD3 every 20 days for 60 days.
Placebo
Treatment - Drugs
Sponsors
Student research committee
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: diagnosis of PCOS based on Rotterdam criteria (presence of two of the three following characteristics: 1. oligomemorreha /amenorrhea, 2. chemical or clinical finding of hyperandrogenism and 3. polycystic appearance of ovary); voluntary consent for participation in the study; female aged 18-40 years. Exclusion criteria: Other common causes of hyperandrogenemia and/or anovulation; hyperprolactinoma; congenital adrenal hyperplasia; Cushing syndrome, and virilizing ovarian or adrenal tumors; diabetes mellitus and heart, kidney and liver dysfunction; using vitamin D or Calcium supplement, metformin or insulin sensitizing drugs, corticosteroids, anticonvulsants during last 2 month or during the study; Smoking; alcohol abuse; breast feeding and pregnancy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of bone biochemical factors. Timepoint: before and after intervention (60 days). Method of measurement: serum levels of alkaline phosphatase, calcium, phosphoruse.;Improvement of serum zinc and magnesium. Timepoint: before and after intervention (60 days). Method of measurement: serum levels of zinc and magnesium. | — |
Secondary
| Measure | Time frame |
|---|---|
| Food habits. Timepoint: before and after intervention (60 days). Method of measurement: 3 days 24h dietaty racall.;Anthropometric indicator. Timepoint: before and after intervention (60 days). Method of measurement: Body weight without shoes with calibrated scale, Standing height without shoes are measuredl. BMI was calculated with this equation: W(kg) /H(m)2. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHania Rahini
Health and Nutrition Faculty, Tabriz university of medical sciences
Outcome results
None listed