Consumption effects of conjugated linoleic acid (CLA) supplementation on oxidative stress and matrix metaloproteinases following exercise in young healthy males

Consumption effects of conjugated linoleic acid (CLA) supplementation on oxidative stress and matrix metaloproteinases after exhaustive training in young healthy males men

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201201035144N3

Enrollment

Registered

2013-06-25

Start date

2013-02-18

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy trained individuals. Examination for participation in sport

Interventions

Intervention 1: Given 5.6 gram/day CLA for14 days and once exhaustive exercise for intervention group. Intervention 2: Giving 5.6 gram oral Paraffin to control group for 14 days and once exhausting ex

Placebo

Given 5.6 gram/day CLA for14 days and once exhaustive exercise for intervention group.

Giving 5.6 gram oral Paraffin to control group for 14 days and once exhausting exercise

Eligibility

Sex/Gender

Male

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Young healthy males with moderate physical activity in 18-30 years old. Exclusion criteria: Individuals with certain diseases, smoking, alcoholism and other supplements, having certain dietary, professional training, sedentary and having 25<BMI<18.5 (body mass index)Kg/m2.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Exhaustion time. Timepoint: At the end of once training. Method of measurement: The signs and symptoms related to the complete exhaustion.	—

Secondary

Measure	Time frame
Oral Paraffin. Timepoint: Two week. Method of measurement: Gram.;Height. Timepoint: At the beginning of intervention. Method of measurement: Stadiometers.;Weight. Timepoint: At the beginning of intervention. Method of measurement: Digital scales.;Malondialdehyde. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Total antioxidant capacity. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Superoxide dismutase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Glutathione peroxidase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Ascorbic acid. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Catalase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Matrix metalloproteinase-2. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Matrix metalloproteinase-9. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Interlukine-6. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Tumor Necrosis factor-alpha. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Hs-CRP. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Immunoturbidimetry.;Paraoxonase-1. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Fasting blood suger. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophoto	—

Measure

Time frame

Oral Paraffin. Timepoint: Two week. Method of measurement: Gram.;Height. Timepoint: At the beginning of intervention. Method of measurement: Stadiometers.;Weight. Timepoint: At the beginning of intervention. Method of measurement: Digital scales.;Malondialdehyde. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Total antioxidant capacity. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Superoxide dismutase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Glutathione peroxidase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Ascorbic acid. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Catalase. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Matrix metalloproteinase-2. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Matrix metalloproteinase-9. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Interlukine-6. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Tumor Necrosis factor-alpha. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: ELISA.;Hs-CRP. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Immunoturbidimetry.;Paraoxonase-1. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophotometry.;Fasting blood suger. Timepoint: At the beginning of intervention, previous and after of exercise. Method of measurement: Spectrophoto

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedyashar Alamolhoda

Ardabil University of Medical Sciences

sy.alam@arums.ac.ir+98 41 1657 8793

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026