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Effect of gargle on sore throat and cough caused by general anesthesia

Effect of lidocaine gargle on sore throat and cough caused by endotracheal intubation in Amir Alam Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201201028589N1
Enrollment
54
Registered
2012-02-22
Start date
2010-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sore throat. Acute pharyngitis

Interventions

Intervention 1: Intervention group gargled 1.5 mg/ kg Lidocaine in 30cc normal saline five minutes before induction of anesthesia for 30 seconds. Intervention 2: 30 cc normal saline was gargled by se
Prevention
Intervention group gargled 1.5 mg/ kg Lidocaine in 30cc normal saline five minutes before induction of anesthesia for 30 seconds
30 cc normal saline was gargled by second group five minutes before induction of anesthesia for 30 seconds

Sponsors

Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients candidate for elective ear surgery under general anesthesia with orotracheal intubation ; ASA physical status class I or II;age between 18 and 80 years old. Exclusion criteria: Patients with operation time less than 60 minute and more than 180 minutes; anticipated difficult intubation; more than twice trying to intubation; NG tube need; upper respiratory tract infection; liver disease; opioid addiction; recent use of pain killers.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sore throat. Timepoint: in PACU and 2, 4 and 12 hours after surgery. Method of measurement: Assessment carried out by trained nurses using the questionnaire.0 :No pain .1:mild pain, 2 : moderate pain, 3: sever pain.

Secondary

MeasureTime frame
Cough. Timepoint: in PACU and 2, 4 and 12 hours after surgery. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Hajimohamadi

Tehran University of Medical Science

hajimoha@sina.tums.ac.ir+98 21 8880 6976

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026