Hemorrhagic Stroke. Intracerebral Haemorrhage, Unspecified
Conditions
Interventions
Intervention 1: Vials of human Albumin 20% : 1 gram per kiloogram body weight divided in 7 days within daily IV infusion during 2 hours. Intervention 2: Saline 0.9% (with an equal volume of 1 gr/kg fr
Treatment - Drugs
Placebo
Saline 0.9% (with an equal volume of 1 gr/kg from human Albumin 20% vial) in 7 days within 2 hours IV infusion
Vials of human Albumin 20% : 1 gram per kiloogram body weight divided in 7 days within daily IV infusion during 2 hours
Sponsors
Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria : Primary Hemorrhagic Stroke; 24 hours from symptom onset; Above 18 years old. Exclusion Criteria : Hematoma volume less than 7 ml; Need surgical evacuation; Pregnancy; Lactation; Systolic blood pressure less than 100 mmHg or more than 250 mmHg; Anticoagulant or Thrombolytic therapy; Serum Creatinine more than 2 mg/dl; History of known allergy to Albumin; History of severe allergic reactions known as latex gloves; Exacerbation of congestive heart failure within the past 6 months; Acute myocardial infarction in the last 6 months.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The hematoma volume. Timepoint: Befor intervention, The end of intervention (One week). Method of measurement: The hematoma volume on CT scan (ml) : Length of maximum appearance of hematoma (cm) × Width of same cut (cm) × Number of cuts including bleeding / 2. | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological deficits. Timepoint: Befor intervention, After one month. Method of measurement: NIHSS criteria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDavood Shalilahmadi, MD
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed