Antifungal Effect of Punica granatum Mouthwash on Oral Candidiasis

The Antifungal Effect of Punica granatum Mouthwash on Oral Candidiasis: a clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120101008585N14

Enrollment

Registered

2022-03-28

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis. Candidal stomatitis

Interventions

Intervention 1: Intervention group: Nystatin oral suspension (100 000 U manufactured by Jaber-ebn-Haian) will be prescribed to swish it for 4 min, gargle, and then expectorate it three times daily for

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Edentulous denture-wearing patients with denture stomatitis

Exclusion criteria

Exclusion criteria: Immunosuppressive patient Diabetic patient The patient who used antibiotic, antifungal medication, or corticosteroid during the last 3 months patients under Chemotherapy or radiotherapy

Design outcomes

Primary

Measure	Time frame
Lesion size. Timepoint: Day 1 and 15 and 30. Method of measurement: Newton's classification.;Candida colony count. Timepoint: Day 1 and 15 and 30. Method of measurement: CFU/ml colony count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Lavaee

Shiraz University of Medical Sciences

lavaeef@sums.ac.ir+98 71 3626 3193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026