The effect of Punica granatum flower tablet on recurrent aphthous stomatitis

Evaluation of the effect of Punica granatum flower tablet on pain and healing of minor recurrent aphthous stomatitis: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120101008585N12

Enrollment

Registered

2022-01-26

Start date

2022-05-21

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent aphthous stomatitis. Recurrent oral aphthae

Interventions

Intervention 1: Intervention group: Patients with recurrent aphthous stomatitis in the experimental group will receive pomegranate flower tablets 3 tablets daily for 7days. Intervention 2: Control gro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Having recurrent aphtus stomatis The participants should not use other routine medication for RAS during the evaluation Less than 24 hours from lesion onset time The participants should not use systemic or topical corticosteroid since 1 month ago.

Exclusion criteria

Exclusion criteria: The participants with other diseases including Behcet disease, Crohn disease, Reiter's syndrome, or any other inflammatory disease The participants who have used analgesic mouthwash or systemic analgesia since 3 days ago pregnant women

Design outcomes

Primary

Measure	Time frame
The amount of pain. Timepoint: Day1,2,3,4,5,6,7 before and after treatment. Method of measurement: Visual anloge scale.;The size of lesion. Timepoint: Day1?2?3?4?5?6?7. Method of measurement: Degreed tongue blade.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Lavaee

Shiraz University of Medical Sciences

lavaeef@sums.ac.ir+98 71 3626 3193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026