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Epidural analgesia and PCA in pain relief after surgery

Analgesic effect and complications of thoracic epidural analgesia compared with IV- PCA(patient controlled analgesia ) in patients under thoracic and upper abdominal surgeries

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201112318566N1
Enrollment
144
Registered
2012-01-31
Start date
2012-01-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain. Acute pain

Interventions

Intervention 1: Intervention in epidural group patients: after the replacement of the intravenous catheter and infusion of 500CC normal saline, 30 minutes before surgery, thoracic epidural catheter 20
Treatment - Drugs
Intervention in epidural group patients: after the replacement of the intravenous catheter and infusion of 500CC normal saline, 30 minutes before surgery, thoracic epidural catheter 20G through 18G ne
Intervention in PCA group: patients will be educated for proper use of PCA system in preoperative and postoperative periods. After surgery, morphine (1mg/ml) to the 2.5 ml (within 10-minute intervals

Sponsors

Hamedan Univercity of Medical Sciences- vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients who were candidate for thoracic or upper abdominal surgeries; between 18 to 70 years old and ASA class2; history of coagulation disorders; allergic reactions to local anesthetic drugs; patient inability for use of PCA pump; presence of significant neurologic disorders in lower limbs and addiction to opioid.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Acute postoperative pain. Timepoint: Every 24 hours to 72 hours. Method of measurement: Measurement of pain as Verbal, VAS.

Secondary

MeasureTime frame
Complications of analgesic method that used for patient. Timepoint: Every 24 hours to 72 hours. Method of measurement: At the time of any symptoms such as itching, nausea and vomiting, significant increase or decreas (over 20%) of blood presure ,respiratory depression and paresthesia or motor weakness of lower limbs.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Vahideh Shahnazari

Hamedan Univercity of Medical Sciences

Shahnazarivahideh@yahoo.com; v.shahnazari_22@yahoo.com+98 81 1264 0020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026