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Sequential regimens in the treatment of Helicobacter pylori

A comparison between sequential therapy versus standard quadruple therapy for Helicobacter pylori eradication in patients attended to firoozgar and rasul hospitals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201112288546N1
Enrollment
160
Registered
2012-04-07
Start date
2012-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Indigestion. Dyspepsia

Interventions

Intervention 1: patients randomly divided into two groups . quadruple therapy for control group was began. 4 drug regimen consisting of omeprazole (20mg BID), amoxicillin 1gr BID)), clarithromycin (5
Treatment - Drugs
patients randomly divided into two groups . quadruple therapy for control group was began. 4 drug regimen consisting of omeprazole (20mg BID), amoxicillin 1gr BID)), clarithromycin (500mg BID), is bi
sequential therapy forcase group was began.Sequential regimen consisting of two stages. Step 1: 7 days of treatment with omeprazole (20mg BID) + amoxicillin (1gr BID) is. Step 2: 7 days of omeprazole

Sponsors

Research Deputy of Tehran University of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria is confirming the diagnosis of H. pylori infection by RUT or histology. Exclusion criteria for this study is allergy to antibiotics.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Response to treatment. Timepoint: 8 weeks after treatment. Method of measurement: UBT test.

Secondary

MeasureTime frame
Intensity and pattern of gastritis. Timepoint: Before treatment. Method of measurement: Observed on endoscopy.;Smoking. Timepoint: Baseline. Method of measurement: Pack /year, The question of the individual.;Body mass index. Timepoint: Baseline. Method of measurement: Kg/m2, With scales and meters.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Saideh Naghibi

Rasool Akram Hospital

saideh.naghibi@gmail.com+98 21 8214 1633

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026