The Efficacy of Golnar on Recurrent Apthous Stomatitis

The Efficacy of Punica Granatum Extract in the Management of Recurrent Apthous Stomatitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112273251N2

Enrollment

Registered

2012-02-07

Start date

2007-03-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent aphthous stomatitis. Recurrent oral aphthae

Interventions

Intervention 1: Golnar, oral gel 10%,three times a day. Intervention 2: placebo, frrous oxid oral gel, three times a day.

Treatment - Drugs

Golnar, oral gel 10%,three times a day

placebo, frrous oxid oral gel, three times a day

Eligibility

Sex/Gender

All

Age

18 Years to 47 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1-patients with minor aphthea; 2-active phase of ulcer (24-48 first hours). Exclusion critria: 1- patients with any systemic disease; 2-patients taking anti-inflammatory or analgesic drugs; 3- patients with major or herpetiform.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: days 0, 1, 3, 5. Method of measurement: VAS.	—

Secondary

Measure	Time frame
The time of complet healing ulcer. Timepoint: during active phase of RAS. Method of measurement: day.;The time of painless ulcer. Timepoint: during active phase of RAS. Method of measurement: day.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Tavangar

Isfahan University of Medical Sciences

tavangar@dnt.mui.ac.ir , dr.tavangar_at@yahoo.com+98 31 1792 2815

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026