Asthma. Asthmatic bronchitis NOS Late-onset asthma
Conditions
Interventions
Intervention 1: Intervention group: 30 milligram of pioglitazone tablet will be given once daily for two months orally to the patients in the intervention group. Intervention 2: Control group: 30 mi
Treatment - Drugs
Intervention group: 30 milligram of pioglitazone tablet will be given once daily for two months orally to the patients in the intervention group
Control group: 30 milligram of placebo tablet will be given once daily for two months orally to the patients in the control group
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion: Asmathic patients; men & women; age range:18-70 years Exclusion: Heart failure; active liver disease including high level of liver enzymes; Edema; Hypersensitivity to pioglitazone; serious drug side effects and/or drug interactions during intervention
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function. Timepoint: before intervention and at the end of it ( 2 months later). Method of measurement: Spirometry test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory biomarkers including TNF alpha And interlukins. Timepoint: before intervention and post intervention (2 months after) ). Method of measurement: quantitative kits with ELIZA reader. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Babak Gholamine
Kermanshah University of medical sciences
Outcome results
None listed