Mood [affective] disorders. Mood [affective] disorders
Conditions
Interventions
Intervention 1: We inject 10microgeram in kilogram intravenous Alfentanil of 10 milliliter and ?Electroconvulsive therapy in intervention group. Intervention 2: We inject 1 milliliter of placebo (Norm
Treatment - Drugs
Placebo
We inject 10microgeram in kilogram intravenous Alfentanil of 10 milliliter and ?Electroconvulsive therapy in intervention group.
We inject 1 milliliter of placebo (Normal saline) and Electroconvulsive therapy ?treatment protocol in control group.
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Hospitalized patients, who have mood disorder confirmed by ?psychiatrist according to DSM-IV-TR criteria and have Electroconvulsive ?therapy indication; ASA I and II; 20 to 60 years??.? Exclusion criteria: Patient's unwillingness to participate in study; pregnancy; ?heart failure; other conditions resulting in myocardial cell damage leading to an ?increase in Troponin I include myocarditis, cardiac surgery, angina, unstable ?angina, congestive heart failure and non-cardiac causes such as kidney failure; ?chronic diseases; musculoskeletal and pulmonary embolism; uncontrolled ?hypertension and hypertension; active gastrointestinal ulcer or bleeding, ?Inflammatory bowel disease; history of severe kidney or liver failure; ?concomitant use of corticosteroids; intracranial hemorrhage or stroke; unstable ?vascular aneurysms; neurological diseases (bulky mass or a history of seizure ?disorders); severe lung problems; ASA class IV and V; smokers with Chronic ?Obstructive Pulmonary Disease; receiving Electroconvulsive therapy in the ?last 2 months.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: Before drug administration, before and after Electroconvulsive therapy ?. Method of measurement: beat per minute.;Mean arterial pressure. Timepoint: Before drug administration, before and after Electroconvulsive therapy ?. Method of measurement: millimeter Hg.;Diastolic blood pressure. Timepoint: Before drug administration, before and after ECT. Method of measurement: mmHg.;Cardiac Troponin. Timepoint: Before drug administration, before and after Electroconvulsive therapy ?. Method of measurement: Micrograms per liter.;Systolic blood pressure. Timepoint: Before drug administration, before and after Electroconvulsive therapy ?. Method of measurement: millimeter Hg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Damanpak Moghaddam
Arak University of Medical Sciences
Outcome results
None listed