constitutional delay of growth and puberty.
Conditions
Interventions
letrofem tab, 2.5mg/day orally for 12 months.
Treatment - Drugs
letrofem tab, 2.5mg/day orally for 12 months
Sponsors
Tehran University of Medical Sciences , Tehran
Iran Hormone Company
Eligibility
Sex/Gender
Male
Age
14 Years to 19 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: The boys are referred to the Endocrine Research Center, for assessment of delayed puberty, short stature, or both,with Tanner genital stage 1 after 13•5 years of age and medical history, clinical examination, or routine laboratory tests all failed to reveal any signs of chronic illnesses accounting for the delayed puberty. Exclusion criteria: The boys are referred to the Endocrine Research Center, for assessment of delayed puberty, short stature, or both,with Tanner genital stage 2 or more after 13•5 years of age and medical history, clinical examination, or routine laboratory tests reveal certain disease as ethology of delayed puberty.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Height and Bone age. Timepoint: 0, 6, 12 and 18 months after study starting. Method of measurement: Bone agecalculated by Greulich ? pyle ,height measure by stadiometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Predicted adult height. Timepoint: 0, 6, 12 and 18 month after start of study. Method of measurement: Calculated by Bayley-pinneau method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farzaneh Rohani
Pediatric Endocrinologist, Endocrine Research Centre (Firouzgar), Institute of Endocrinology and Met
Outcome results
None listed