Condition 1: Change in heart rate caused by anesthesia induction. Condition 2: Change in blood pressure caused by anesthesia induction. Bradycardia, unspecified Hypotension, unspecified
Conditions
Interventions
Intervention 1: In the group Ketofol, ketamine 0.75 mg/kg and propofol 1 mg/kg would be administered intra-venously to induct the anesthesia. Plus, Ketamine 0.25 mg/kg and propofol 1 mg/kg would be pr
Prevention
In the group Ketofol, ketamine 0.75 mg/kg and propofol 1 mg/kg would be administered intra-venously to induct the anesthesia. Plus, Ketamine 0.25 mg/kg and propofol 1 mg/kg would be prepared to be adm
In the group Etofol, etomidate 0.2 mg/kg and propofol 1 mg/kg will be administered intra-venously to induct the anesthesia. Plus, Etomidate 0.1 mg/kg and propofol 1 mg/kg would be prepared to be admin
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: to have indication for elective surgeries; to be 50 or over 50 years old. Exclusion criteria: to have indication for emergency surgery; addiction to opiate; pregnancy; patients being treated with sedative or antipsychotic drugs in the past month; to have a personality disorder; to have body weight more than 20% of the ideal body weight for that height and gender; to have contraindication for etomidate, ketamine and propofol
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: Before and immediately after induction, 1 and 3 minutes after intubation. Method of measurement: Non-invasive monitoring device with automatic cuff.;Heart rate. Timepoint: before and immediately after induction, 1 and 3 minutes after intubation. Method of measurement: Continuous ECG monitoring.;Blood O2 saturation. Timepoint: before and immediately after induction, 1 and 3 minutes after intubation. Method of measurement: pulse oximetry.;Diastolic blood pressure. Timepoint: before and immediately after induction, 1 and 3 minutes after intubation. Method of measurement: Non-invasive monitoring device with automatic cuff.;Mean arterial blood pressure. Timepoint: before and immediately after induction, 1 and 3 minutes after intubation. Method of measurement: non-invasive monitoring devices with automatic cuff. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahmoud Vasebi
Tabriz University of Medical Sciences
Outcome results
None listed