Evaluation of the effect of Oxytetracycline spray in treatment of diabetic foot ulcers

Evaluation of the effect of Oxytetracycline Spray in treatment of diabetic foot ulcers

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112208472N1

Enrollment

Registered

2012-06-10

Start date

2010-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Diabetic Foot Ulcer. Condition 2: Diabetic Foot Ulcer. Insulin-dependent diabetes mellitus With peripheral circulatory complications Non-insulin-dependent diabetes mellitus with peripheral circulatory complications

Interventions

Intervention 1: Oxytetracycline spray (contains 4.2 gr Oxytetracycline Hydrochloride,420 mg Gentian Violet and 210 ml Excipients and Propellant qs) Spray two times a day from a distance of 15 -20 cm l

Treatment - Drugs

Oxytetracycline spray (contains 4.2 gr Oxytetracycline Hydrochloride,420 mg Gentian Violet and 210 ml Excipients and Propellant qs) Spray two times a day from a distance of 15 -20 cm localy at ulcer a

standard wound care for diabetic foot ulcer (glycemic control, debridement, dressing, offloading and infection control)

Eligibility

Sex/Gender

All

Age

43 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Presence of diabetes mellitus type 1 or 2; presence of ulcer on foot Extremities( grade II foot ulcer based on the Wagner wound classification); sutured ulcers with infection possibility; reconstruction dysfunction. Exclusion criteria: patients not willing to voluntary cooperation; patients not willing for treatment; severe perfusion dysfunction(ABI2.5)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Wound surface area. Timepoint: Baseline, after 1,2,3 and 4 weeks. Method of measurement: To determine this outcome, digital photograph will be taken(by Digital camera Dino – lite AM-413 ) and the wound surface area will be determined using special software (Hakim Software) through planimetry methods(?cm?^2.	—

Secondary

Measure	Time frame
Wound healing. Timepoint: baseline,week 1.2.3 and 4. Method of measurement: Clinical evaluation of wound for erythema, swelling and pus discharge.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEmad Ebrahimi

Mashhad University of Medical Science

ebrahimie841@mums.ac.ir+98 51 1891 5540

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026