A Comparison between neostigmin and ketamin as adjvant with bupivacain 0.25% in epidural method for post oparative pain control in patient with femoral fracture and candidate for elective surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112198468N1

Enrollment

Registered

2012-04-25

Start date

2012-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femor Fracture Sergery. Fracture of femur

Interventions

Intervention 1: group A

neostigmine 60 mcg added to 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin. Intervention 2: group B

KETAMIN 40 mg added to 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin. Intervention 3: group C

only 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin.

Treatment - Drugs

group A

neostigmine 60 mcg added to 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin

group B

KETAMIN 40 mg added to 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin

group C

only 2cc/segment of 0.25% bopivacaine in atotal volume 20cc with water for injectin

Eligibility

Sex/Gender

All

Age

50 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Age above 50 y/o, ASA class 1 and 2, Elective sergury candidate, No sensitivity to local anesthetic, No contrandication to rgional anesthesia, Exclusion criteria: Sergury above 2hours, Failuer of epidural anesthesia, Concomitant fracture, Fever and infection

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain Scre. Timepoint: During serger, in recovery,6and 12 and 24 hours after sergery. Method of measurement: Visual Analog Sore.	—

Secondary

Measure	Time frame
Vital Sign: BP,HR PR O2Sat,ECG. Timepoint: During serger,in recovery,6and 12 and 24 hours after sergery. Method of measurement: Electronic Monitoring Device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Abbas Zareei

Arak Univesity Of Medical Sciences

dr.zarei@arakmu.ac.ir+98 86 1223 1103

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026