The effect of Nano-silver (Agicoat) dressing on wound healing

Comparing the effect of Nano-silver (Agicoat) and Mepitel dressing on healing of skin graft donor site

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112188177N2

Enrollment

Registered

2013-09-02

Start date

2013-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin Wound. Open wound of unspecified body region

Interventions

Intervention 1: Intervention 1: Coverage of the skin graft donor site with Nano-silver dressing (Agicoat, Emad Pharmacological Institute) . The dressing will not be disturbed till 4th post operative d

Treatment - Other

Intervention 1: Coverage of the skin graft donor site with Nano-silver dressing (Agicoat, Emad Pharmacological Institute) . The dressing will not be disturbed till 4th post operative day and then will

Intervention 2: Coverage of the skin graft donor site with Mepitel dressing (Mölnlycke Health Care Company) . The dressing will not be disturbed till 4th post operative day and then will be changed ev

Control group: Coverage of the skin graft donor site with Vaselie gauze.The dressing will not be disturbed till 4th post operative day and then will be changed every 4 days, till complete healing.

Eligibility

Sex/Gender

All

Age

16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.Sixteen to sixty years old patients 2.Needing skin graft surgery 3.Filling informed consent Exclusion criteria: 1.Co - morbidity 2.Sensitivity to silver

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Wound healing. Timepoint: Examination and photography on 4, 8, 12, 16 days and 1 month after surgery. Method of measurement: Examination, Photography.;Cost. Timepoint: After ending intervention. Method of measurement: Calculation of dressing costs per group.	—

Secondary

Measure	Time frame
Scar. Timepoint: Six months after beginning of intervention. Method of measurement: Vancouver Scar Scale.;Pain. Timepoint: Four, eight, twelve, and sixteen days after surgery. Method of measurement: Visual Analogue Scale.;Infection. Timepoint: If necessary, on 4, 8, 12 and 16 days after surgery. Method of measurement: Examination, Wound Culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Javad Fatemi

Hazrat Fatima Hospital

mj-fatemi@sina.tums.ac.ir+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026