Treatment of unruptured tubal pregnancy. Treatment of unruptured ectopic pregnancy
Conditions
Interventions
Intervention 1: In the study group, single dose regimen, 50mg /m2 intramuscular methotrexat. Intervention 2: In the control group, Intramuscular methotrexate (1mg/kg/day) was given on days 1,3,5,7 and
Treatment - Drugs
In the study group, single dose regimen, 50mg /m2 intramuscular methotrexat
In the control group, Intramuscular methotrexate (1mg/kg/day) was given on days 1,3,5,7 and citrovoram factor (0.1mg/kg/day) were administered for 2,4,6,8 days
Sponsors
Vice chancellor for research, Shahid Sadughi University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria gestational age less than 20 weeks; absence of bleeding in evidences of laparoscopic surgery and vaginal sonography; stable hemodynamic state; tubal mass equal or less than 4 cm in diameter; absence of fetal heart beat; ß -hCG less than 15000 mlU/mL, and leaning of patient to next pregnancy. Exclusion criteria Creatinine levels more than 1.5 mg/kg, Platelet levels more than 100000/ml, W.B.C levels more than 2000/ml, Higher than 2 times increased liver enzyme levels
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rates of treatment. Timepoint: Interval 48 hrs. on days 1,3,5,7. Method of measurement: Measurement of ß - hCG level. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fertility. Timepoint: 12 months after treatment. Method of measurement: Question about fertility. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfsar Tabatabaii Bafghi
Shahid Sadughi Hospital
Outcome results
None listed