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A comparison of the efficacy of Plavix and Osivix in patients undergoing Coronary artery by pass

A comparison of the effectiveness, side effects and acceptability of Plavix and Osivix as anti platelet tablets in patients undergoing Coronary artery by pass.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201112178428N1
Enrollment
80
Registered
2014-04-19
Start date
2012-02-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart disease. Other functional disturbances following cardiac surgery

Interventions

Intervention 1: at this clinical trial study, the control group consists of 40 patients recieve Plavix tablets as an antiplatetlet agent. The prescribed dose is 75 mg of Clopidogrel per day for each
Treatment - Drugs
at this clinical trial study, the control group consists of 40 patients recieve Plavix tablets as an antiplatetlet agent. The prescribed dose is 75 mg of Clopidogrel per day for each group. It shoul
at this clinical trial study, the intervantion group consists of 40 patients recieve Osvix tablets as an antiplatetlet agent. The prescribed dose is 75 mg of Clopidogrel per day for each group. It s

Sponsors

Research Deputy of Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients undergoing open heart surgery Exclusion criteria: 1- Patients with a prior events of acute coronary syndrome, 2- Hepatic insufficiency, 3- History of significant bleeding disorder,4- Those already taking anti-platelet and/or anticoagulant therapy, 5- Age less than 20 and over than 75.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Platelet-rich plasma. Timepoint: 30 days after heart surgery. Method of measurement: Aggregometry.

Secondary

MeasureTime frame
Adenosine diphosphate. Timepoint: 30 days after heart surgery. Method of measurement: Aggrigometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Imani

Hamadan University of Medical Sciences

b.imani@umsha.ac.ir+98 81 1838 1017

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026