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Comparison of the effects of oral acetazolamide versus Cosopt drops to prevent increase in intraocular pressure after YAG laser in posterior capsulotomy

Comparison of the effects of oral acetazolamide versus Cosopt drops to prevent increase in intraocular pressure after YAG laser in posterior capsulotomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201112148410N1
Enrollment
200
Registered
2012-01-01
Start date
2011-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular hypertension. Glaucoma suspect: Ocular hypertension

Interventions

Intervention 1: First group, will receive oral acetazolamide 250 mg/6h and placebo drops every 8h after capsulotomy with laser for 24 hours. Intervention 2: Second group, will receive Cosopt drops eve
Treatment - Drugs
First group, will receive oral acetazolamide 250 mg/6h and placebo drops every 8h after capsulotomy with laser for 24 hours.
Second group, will receive Cosopt drops every 8h and oral placebo capsule every 6h after capsulotomy with laser for 24 hours.

Sponsors

Arak University of Medical Sciences, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. age over 40 years; 2. phacoemulsification surgery at least 3 months ago; 3. To have posterior capsule opacity; 4. patient should be operated by phacoemulsification method. Exclusion criteria: 1. asthma and pulmonary obstructive diseases; 2. medication side effects; 3. Retinopathy; 4. severe corneal opacity; 5. occurrence of intraoperative complications; 6. history of glaucoma; 7. Uveitis; 8. absence in the follow up; 9. traumatic cataract.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ocular hypertension. Timepoint: before capsulotomy surgery and 24 hours after capsulotomy surgery. Method of measurement: Goldmann tonometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ahamad Sarvarian

Arak University of Medical Sciences

dr.ahsarvarian@arakmu.ac.ir+98 86 1313 5075

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026