Septic shock. R57.2
Conditions
Interventions
Intervention 1: In the intervention group, 5% hypertonic saline is prescribed at the rate of 5 cc per kg of body weight at the beginning of septic shock treatment. Intervention 2: In the control group
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with septic shock, Age between 80-18 years
Exclusion criteria
Exclusion criteria: Patient dissatisfaction, Patients with incurable disseminated malignancy, Patients with hypernatremia, Patients receiving colloidal solutions such as albumin, etc. Any volume-limiting restrictions such as irreversible heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters (heart rate, mean arterial pressure, systolic blood pressure, diastolic blood pressure, central venous pressure). Timepoint: At the beginning of the patient's study and in the first, second and third hours of the intervention. Method of measurement: Hemodynamic parameters by monitoring device andCentral venous pressure rulers are measured. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1- Gasometric parameters 2- Optical nerve diameter. Timepoint: At the beginning of the patient's study and in the first, second and third hours of the intervention (optic nerve diameter at the beginning and the third hour of the intervention), they are measured, recorded and compared. Method of measurement: Gasometer and sonography device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Peyvandi Yazdi
Mashhad University of Medical Sciences
Outcome results
None listed