osteoarthritis. Primary generalized (osteo)arthrosis
Conditions
Interventions
Intervention 1: Ginger group took the capsules 500 mg (ginger powder as drug) 2 times a day. Duration of this intervention was 3 months. Intervention 2: Placebo group took the capsules 500 mg (starch
Treatment - Drugs
Placebo
Ginger group took the capsules 500 mg (ginger powder as drug) 2 times a day. Duration of this intervention was 3 months.
Placebo group took the capsules 500 mg (starch powder) 2 times a day. Duration of this intervention was 3 months.
Sponsors
Yazd University of Medical Scieces
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: to complete the inform consent; the presence of medium knee pain between 40mm and 70 mm on a 100-mm visual analog scale (VAS) during the preceding 24 hours; the age between 50 and 70 years; absence of following conditions: inflammatory disease, metabolic disorder such as diabetes, dementia, rheumatoid arthritis, fibromyalgia, gout, cancer or other serious disease, signs or history of liver or kidney failure, asthma requiring treatment with steroids; treatment with oral corticosteroids within the prior 4 weeks; intraarticular knee depo-corticosteroids within the previous 3 months; prior treatment with immunosuppressive drugs such as penicillamine; arthroscopy of the target joint within the previous yea; significant injury to the target joint within the previous 6 months; fever >38 degree C at screening; allergy to ginger. Exclusion criteria: serious complications; consumption of vitamin-mineral supplements or other nutritional supplements; consumption of analgesics.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: before the intervention and 12 weeks after the end of treatment. Method of measurement: visual analoge scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Some pro-inflammatory cytokins. Timepoint: before the intervention and after 12 weeks. Method of measurement: ELISA kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Naderi
Shahid Sadooghi university of medical sciences
Outcome results
None listed