selenium in the prevention of pre-procedural myocardial injury in patients undergoing angioplasty

Randomized trial of selenium in the prevention of pre-procedural myocardial injury in patients undergoing angioplasty

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20111206008307N30

Enrollment

100

Registered

2018-12-27

Start date

2018-09-23

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic heart diseases patients. Ischaemic heart diseases

Interventions

Intervention 1: Intervention group: intervention group will recieve 1000 microgram selenium dose with standard treatments control group will only recieve standard treatments and placebo. Intervention

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Ischemic heart diseases and diabetic patients; age 18-85; undergoing of angioplasty with stent insertion; filling of consent form

Exclusion criteria

Exclusion criteria: Elevation of CK-MB and cTnI before PCI; history of CABG during last three months; history of previous MI; renal dysfunction (creatinine above 2.5 mg/dl); unsuccessful PCI; acute MI; cardiogenic shock; dialysis; pregnancy; inability in filling and understanding of the consent form; unconsented patients; patients who want to discontinue the study at any time.

Design outcomes

Primary

Measure	Time frame
CK-MB level. Timepoint: 12 hours Before, 8 and 24 hours after angioplasty. Method of measurement: ELISA.;CTnI level. Timepoint: Before, 8 and 24 hours after angioplasty. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Taher Entezari-Maleki

Tabriz University of Medical Sciences

tentezari@gmail.com+98 413344798

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026