Comparing the effects of supplementation Krstyn, Vitamin C, endothelial function, oxidative stress, exercise performance, Indicators of inflammation and muscle damage in athletes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112055062N4

Enrollment

Registered

2011-12-23

Start date

2011-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sport medicine.

Interventions

Intervention 1: Control Group: Group 4: 1 capsule of 500 mg Krstyn placebo tablet daily and a placebo vitamin C tablet. Intervention 2: Intervention group: Group 1: 1 capsule of 500 mg Krstyn suppl

Treatment - Drugs

Control Group: Group 4: 1 capsule of 500 mg Krstyn placebo tablet daily and a placebo vitamin C tablet

Intervention group: Group 1: 1 capsule of 500 mg Krstyn supplement daily and 1 tablet of 250 mg vitamin C

Intervention group: Group 2: one capsules of 500 mg Krstyn supplements daily and a placebo tablet of vitamin C

Intervention group: Group 3: daily, one capsule of 500 mg Krstyn placebo and 1 vitamin C tablets

Eligibility

Sex/Gender

Male

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: willingness to participate in the study, male, students of Isfahan University of Medical Sciences, a history of continuous exercise at least 3 years of experience, the use of antioxidant supplements in the previous month Exclusion criteria: less than 70% adherence, presence of diseases requiring special treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
VO2max. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;Traveled distance. Timepoint: before and after intervention. Method of measurement: gaz analysor.;Time to reach fatigue. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;Heart rate. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;SVCAM. Timepoint: before and after intervention. Method of measurement: Elisa.;PAI-1. Timepoint: before and after intervention. Method of measurement: Elisa.;SICAM-1. Timepoint: before and after intervention. Method of measurement: Elisa.;E-selectin. Timepoint: before and after intervention. Method of measurement: Elisa.;Crp. Timepoint: before and after intervention. Method of measurement: elisa.;F2-Isoprostane. Timepoint: before and after intervention. Method of measurement: elisa.;Blood lactic acid. Timepoint: before and after intervention. Method of measurement: lactometer.;IL-1B. Timepoint: before and after intervention. Method of measurement: Elisa.;IL-2. Timepoint: before and after intervention. Method of measurement: elisa.;IL-6. Timepoint: before and after intervention. Method of measurement: Elisa.;TNF-a. Timepoint: before and after intervention. Method of measurement: Elisa.;CK. Timepoint: before and after intervention. Method of measurement: Chimical coloremetric.;ASP. Timepoint: before and after intervention. Method of measurement: PHOTOMETERIC.	—

Measure

Time frame

VO2max. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;Traveled distance. Timepoint: before and after intervention. Method of measurement: gaz analysor.;Time to reach fatigue. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;Heart rate. Timepoint: before and after intervention. Method of measurement: Gas Analyzor.;SVCAM. Timepoint: before and after intervention. Method of measurement: Elisa.;PAI-1. Timepoint: before and after intervention. Method of measurement: Elisa.;SICAM-1. Timepoint: before and after intervention. Method of measurement: Elisa.;E-selectin. Timepoint: before and after intervention. Method of measurement: Elisa.;Crp. Timepoint: before and after intervention. Method of measurement: elisa.;F2-Isoprostane. Timepoint: before and after intervention. Method of measurement: elisa.;Blood lactic acid. Timepoint: before and after intervention. Method of measurement: lactometer.;IL-1B. Timepoint: before and after intervention. Method of measurement: Elisa.;IL-2. Timepoint: before and after intervention. Method of measurement: elisa.;IL-6. Timepoint: before and after intervention. Method of measurement: Elisa.;TNF-a. Timepoint: before and after intervention. Method of measurement: Elisa.;CK. Timepoint: before and after intervention. Method of measurement: Chimical coloremetric.;ASP. Timepoint: before and after intervention. Method of measurement: PHOTOMETERIC.

—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026