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A Comparison of Granisetron and Metoclopramide in the treatment of nausea and vomiting in patients with migraine headache

A Comparision of Granisetron and Metoclopramide in the treatment of nausea and vomiting in patients with migraine headache

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201112038292N1
Enrollment
150
Registered
2013-01-31
Start date
2011-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

migraine headache. Migraine

Interventions

Intervention 1: In case group the patients received 2 mg granicetrone single dose intravenously. Intervention 2: In control group the patients received 10 mg metoclopramide single dose intravenously.
Treatment - Drugs
In case group the patients received 2 mg granicetrone single dose intravenously
In control group the patients received 10 mg metoclopramide single dose intravenously

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: Patients older than 18 presenting with migraine headache to sina and rasool akram emergency; Have a previous history of migraine headache which was diagnosed by a neurologist; Not being pregnant; No breast feeding; No history of psychiatric disorder in the patient or first degree relatives exclusion criteria: Patient's incoopration; Headache's charectristics is different from previus attacks; Sudden oncet headache; Abnormal neurologic exam; uncertainity in diagnosis; Head trauma in the previous month

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Number of nausea and vomiting episodes. Timepoint: Before, 1, 2, 4 hours after intervention. Method of measurement: Standard Questionnaire.

Secondary

MeasureTime frame
Headache intensity. Timepoint: Before, 1, 2, 4 hours after intervention. Method of measurement: Verbal numerical rating scale.;Adverse effects. Timepoint: Before, 1, 2, 4 hours after intervention. Method of measurement: Standard Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hasan amiri MD

Tehran university of medical sciences

h_amiri@sina.tums.ac.ir+98 21 63120

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026