Comparison of depth of anesthesia in patients under general anesthesia with Propofol or Isoflurane undergoing total abdominal hysterectomy with bispectral index

Comparison of depth of anesthesia in patients under general anesthesia with Propofol or Isofluran undergoing total abdominal hysterectomy with bispectral index

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201112024969N5

Enrollment

Registered

2012-01-15

Start date

2011-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depth of anesthesia and blood pressure. -

Interventions

Intervention 1: Anesthesia with Isoflorane as 0.6 to 1.4 % of inspiratory gas. Intervention 2: Anesthesia with intravenous Propofol infusion 100 to 200 microgram per kilogram body weight.

Treatment - Other

Anesthesia with Isoflorane as 0.6 to 1.4 % of inspiratory gas

Anesthesia with intravenous Propofol infusion 100 to 200 microgram per kilogram body weight

Eligibility

Sex/Gender

Female

Age

35 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:women ASA I,II candidate for total abdominal hysterectomy. Exclusion criteria: Ages less than 35 and more than 65 years old; history of cardiac disease; hypertension; diabetes; renal or hepatic disease; no history of allergy to egg or propofol in previous anesthesia(if she had); heart rate and blood pressure changes more than 30% of baseline; any vasoactive or vasodilator injection requirement more than expected in protocol.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depth of anesthesia. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: number from 100, by BIS.;Systolic blood pressure. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: automatic.;Diastolic blood pressure. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: automatic.;Heart rate. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: puls oxymeter.	—

Measure

Time frame

Depth of anesthesia. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: number from 100, by BIS.;Systolic blood pressure. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: automatic.;Diastolic blood pressure. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: automatic.;Heart rate. Timepoint: at the beginning of anesthesia,then every 30 minutes. Method of measurement: puls oxymeter.

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Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026