Chronic renal failure. Renal failure
Conditions
Interventions
Intervention 1: Ondansetron tablets 8 mg three times daily for two weeks in the intervention group. Intervention 2: Loratadine tablets 10 mg twice daily in the control group.
Treatment - Drugs
Placebo
Ondansetron tablets 8 mg three times daily for two weeks in the intervention group
Loratadine tablets 10 mg twice daily in the control group
Sponsors
Vice chancellor for research and education
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with chronic renal failure undergoing hemodialysis; willingness of patients for entry into the study; minimum age 18 years. Exclusion criteria: Patients with a history of skin or metabolic disease causing itching; Patients who received anti-pruritic medications two weeks before; pregnant women; People under age 18; non-cooperation Patients.
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Side effect. Timepoint: During the intervention. Method of measurement: Visual and laboratory. | — |
Primary
| Measure | Time frame |
|---|---|
| Pruritus. Timepoint: Baseline - A week later, two weeks after the intervention. Method of measurement: VAS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mina Mirnezami
Arak University of Medical Sciences
Outcome results
None listed