Efficacy of adding Ketamine to Ropivacaine in continues femoral nerve block

Effectiveness of adding Ketamine to Ropivacaine in continues femoral nerve block for postoperative pain control in anterior cruciate ligament reconstruction surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111278221N1

Enrollment

Registered

2013-02-23

Start date

2010-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ant cruciate ligament strain. Sprain and strain involving (anterior)(posterior) cruciate ligament of knee

Interventions

Intervention 1: Femoral block with 0.3 cc/kg Ropivacaine %0.2 performed and femoral catheter for continues infusion of medication with pump inserted and 100 cc Ropivacaine %0.2 was placed in infusion

infusion rate was 5cc/hour. Intervention 2: Femoral block with 0.3 cc/kg Ropivacaine %0.2 performed and femoral catheter for continues infusion of medication with pump inserted and 100cc Ropivacaine %

infusion rate was 5cc/hour. Pumps were refilled if they were finished.

Treatment - Drugs

Femoral block with 0.3 cc/kg Ropivacaine %0.2 performed and femoral catheter for continues infusion of medication with pump inserted and 100 cc Ropivacaine %0.2 was placed in infusion pump

infusion rate was 5cc/hour.

Femoral block with 0.3 cc/kg Ropivacaine %0.2 performed and femoral catheter for continues infusion of medication with pump inserted and 100cc Ropivacaine %0.125 with Ketamine 1mg/kg was placed in inf

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1) Age 15 to 60 years; 2) ASA I & II; 3) candidates for elective knee surgery; 4) Written consent. Exclusion Criteria: 1) A history of drug misuse; 2) Allergy to Ketamine and Ropivacaine; 3) Alcohol and drugs abuse; 4) Pregnancy and breast feeding; 5) Refusing patients studied; 6) Infection in block area; 7) Any neuropathy; 8) Diabetes; 9) Cardiovascular disease; 10) Hypertension; 11) Renal insufficiencies; 12) Liver failure.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Motor block. Timepoint: 48 hours after surgery. Method of measurement: based on Quadriceps muscle weakness.;Pain. Timepoint: 48 hours after surgery. Method of measurement: based on VAS.	—

Secondary

Measure	Time frame
Opioid requirment. Timepoint: 48 hours after surgery. Method of measurement: Based on miligram of opioid required.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Hamidreza Faiz

Tehran university ofmedical sciences

hrfaiz@hotmail.com+98 21 64351

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026