The Comparison of three methods of endotracheal tube cuff pressure regulation on ventilator-associated pneumonia

The Comparison of three methods of endotracheal tube cuff pressure regulation in patients with mechanical ventilation on incidence of ventilator-associated pneumonia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111256481N2

Enrollment

Registered

2011-12-12

Start date

2012-02-10

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with mechanical ventilation. Pneumonitis due to food and vomit

Interventions

Intervention 1: Group1: regulation of edotracheal tube cuff pressure with estimation method. Intervention 2: Group2: regulation of edotracheal tube cuff pressure with minimal leak method. Interventio

Prevention

Group1: regulation of edotracheal tube cuff pressure with estimation method.

Group2: regulation of edotracheal tube cuff pressure with minimal leak method.

Group3: regulation of edotracheal tube cuff pressure with manometer method.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18-65 years; Orotracheal tube; Expectation for mechanical ventilation for more than 72 hours. Exclusion criteria: Patients with tracheostomy tube; dying or disconnection from mechanical ventilation before completing study; Immune system suppression; approved pneumonia before start of study; massive aspiration; malignancy; reintubation; change in cuff pressure out of study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ventilator Associated Pneumonia. Timepoint: Before intervention and 4 days later. Method of measurement: Clinical pneumonia index.	—

Secondary

Measure	Time frame
Administration time in ICU. Timepoint: From administration to discharge. Method of measurement: Counting.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Soleimani

Semnan University of Medical Sciences

soli257@yahoo.com+98 23 1335 4190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026