Hypopigmented scar. Other disorders of diminished melanin formation
Conditions
Interventions
Intervention 1: Intervention group 1: Needling procedure is performed under local anesthesia on the hypopigmented or depigmated organs of the patient, measuring from 4 to 25 cm square. The German AMIE
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients aged 15-50 years. In two symmetrical regions of the body (focusing on the organs) having hypopigmented scars. Willing to cooperate and follow-up on treatment and complete the informed consent form.
Exclusion criteria
Exclusion criteria: Patients who are pregnant, are planning to become pregnant, or are breastfeeding. Those who have had severe systemic diseases in the past 6 months. Concomitant diseases (diabetes, connective tissue disease, chronic kidney disease, cardiovascular disease) and any type of disease that can cause immune system dysfunction and delay wound healing. Immunosuppressant drugs and corticosteroids. History of the use of depigmented or pigmented products on scars during the past 3 months. Have a history of allergy or high sensitivity to the compounds used in the study. Smoking and alcohol consumption. Since the onset of a lesion leading to hypopigmented or depigmented scars, only 6 months have passed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scar. Timepoint: Before intervention, 3 and 6 months after using the last dose of drops. Method of measurement: 0-4 scale (including resizing and colorimetric staining) and Vancouver Scar scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction. Timepoint: Before intervention, 3 and 6 months after using the last dose of drops. Method of measurement: Visual Analog Scale.;Cost. Timepoint: The end of the study. Method of measurement: Estimated cost of microneedling process and latanoprost drops. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahnoush Momeni
Iran University of Medical Sciences
Outcome results
None listed