The effect of laser therapy in the treatment of hemorrhoids

Evaluation of the effectiveness of photobiomodulation in improving symptoms and treating patients with grade I, II, and III hemorrhoids

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20111121008146N48

Enrollment

Registered

2025-04-15

Start date

2025-05-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Grade I hemorrhoids. Condition 2: Grade II hemorrhoids. Condition 3: Grade III hemorrhoids. First degree hemorrhoids- Second degree hemorrhoids Third degree hemorrhoids

Interventions

Intervention group: 30 patients with grade 1, 2, and 3 hemorrhoids will undergo treatment with transrectal photobiomodulation using a GaAlAs semiconductor diode laser with a wavelength of 650 nanomete

Eligibility

Sex/Gender

All

Age

18 Years to 95 Years

Inclusion criteria

Inclusion criteria: Adults 18 to 95 years old with a diagnosis of hemorrhoids by a gastroenterologist

Exclusion criteria

Exclusion criteria: Contraindications for low-level laser therapy Previous treatment Grade 4 hemorrhoids

Design outcomes

Primary

Measure	Time frame
Severity of bleeding. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Physical examination by a specialist.;Hemorrhoid prolapse. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Physical examination by a specialist.;Itching and burning sensation. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Hemorrhoidal disease symptoms score questionnaire.;Pain. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Hemorrhoidal disease symptoms score questionnaire.	—

Measure

Time frame

Severity of bleeding. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Physical examination by a specialist.;Hemorrhoid prolapse. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Physical examination by a specialist.;Itching and burning sensation. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Hemorrhoidal disease symptoms score questionnaire.;Pain. Timepoint: Before and after treatment - 4 weeks after completing the treatment. Method of measurement: Hemorrhoidal disease symptoms score questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Razzaghi

Shahid Beheshti University of Medical Sciences

morezarazaghi@gmail.com+98 21 2271 8001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026