Comparison of laser and ozone injection in pain control of knee bone infection

Comparison effect of Biolaser and intra-articular Ozone injection in knee pain management in patients with knee osteoarthritis with ultrasound guidance

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20111121008146N15

Enrollment

Registered

2018-01-01

Start date

2017-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The pain of knee osteoarthritis. Osteopathies in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: 20 ml normal saline + 5 ml lidocaine 1% + bio laser + physiotherapy. In supine position, with knee flexion of 45-30 ° on the lateral side of the knee, injection sit

Treatment - Devices

Placebo

Intervention group: 20 ml normal saline + 5 ml lidocaine 1% + bio laser + physiotherapy. In supine position, with knee flexion of 45-30 ° on the lateral side of the knee, injection site with Povidone

Control group: 20 ml of ozone (15 µg / ml) + 5 ml lidocaine 1% + placebo bio laser + physiotherapy. In a supine position, with knee flexion of 30-45 degrees on the lateral side of the knee, place the

Eligibility

Sex/Gender

All

Age

40 Years to No maximum

Inclusion criteria

Inclusion criteria: Having the consent to participate in the project Age 40 and older The pain of knee osteoarthritis for more than three months Radiological findings confirming knee osteoarthritis based on American College of Rheumatology (ACR) 31

Exclusion criteria

Exclusion criteria: Patients with dissatisfaction in participation in the project History of knee surgery Deformity and lower limb contraction Neuromascular disease of the lower limb Acute lumbosacral pathology Injection of steroid medications in the last two months History of inflammatory rheumatoid arthritis Infection Diabetes Pregnancy Lactation BMI>35 patients with knee surgery Knee deviation (varrous or valgus more than 5 degrees) confirmed by three joint view Radicular pain knee Anticoagulant therapy Post-traumatic arthritis History of injection Intraarticular or ozone therapy over the past 12 months Systemic or psychiatric illness Severe osteoarthritis with Grade over III

Design outcomes

Primary

Measure	Time frame
Pain of knee. Timepoint: Before starting treatment, one month and three months after the last. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sirous Momenzadeh

Shahid Beheshti University of Medical Sciences

laser.cntr@yahoo.com+98 21 2274 9221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026