The effect of sodium and ultrafiltration profiles on preventing from the complications made during hemodialysis

Combined effect of sodium and ultrafiltration profiles on some of the common complications during hemodialysis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111208140N1

Enrollment

Registered

2012-03-05

Start date

2012-01-14

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage kidney disease. End stage kidney disease

Interventions

Intervention 1: For each group in this research, four different hemodialysis protocols are implemented. These protocols are as follows: Protocol 1: Linear Sodium Dialysate (150 - 138mEq/L) and constan

Prevention

For each group in this research, four different hemodialysis protocols are implemented. These protocols are as follows: Protocol 1: Linear Sodium Dialysate (150 - 138mEq/L) and constant Ultra?ltration

For Group B, protocols, 2-3-4 and 1 run respectively.

For Group C, protocols, 3-4-1 and 2 run respectively.

For Group D, protocols, 4-1-2 and 3 run respectively.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: hemodialysis patients in Panje Azar Hospital of Gorgan, who have: 1- hypotension for more than three sessions during last month (20 percent of the sessions). 2- Age of 18-75 years. 3- hemodialysis for more than three months. 4- Dialysis for three times a week with a solution of sodium bicarbonate. 5- End-stage renal diseases. Exclusion criteria: The patients, 1- Before starting dialysis, having systolic blood pressure of below 100 mm Hg. 2- Patients with complications studied in this project (cramps, nausea, vomiting and headache). 3- Administered analgesic, anti-hypertensive and anti-spasmodic, four hours before of dialysis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: pre, intra & post dialysis. Method of measurement: Blood pressure based on mm Hg, monitoring by Gambro AK96 dialysis machine.;Muscle cramps. Timepoint: pre, intra & post dialysis. Method of measurement: checklist.;Nausea & vomiting. Timepoint: pre, intra & post dialysis. Method of measurement: with checklist.;Headache. Timepoint: pre, intra & post dialysis. Method of measurement: with checklist.	—

Measure

Time frame

Blood pressure. Timepoint: pre, intra & post dialysis. Method of measurement: Blood pressure based on mm Hg, monitoring by Gambro AK96 dialysis machine.;Muscle cramps. Timepoint: pre, intra & post dialysis. Method of measurement: checklist.;Nausea & vomiting. Timepoint: pre, intra & post dialysis. Method of measurement: with checklist.;Headache. Timepoint: pre, intra & post dialysis. Method of measurement: with checklist.

—

Secondary

Measure	Time frame
Urea. Timepoint: pre & post dialysis. Method of measurement: Laboratory method.;Sodium plasma. Timepoint: pre & post dialysis. Method of measurement: Laboratory method.;Plasma osmolality. Timepoint: pre & post dialysis. Method of measurement: Laboratory method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEinollah Mollaei

Golestan University of Medical Sciences

Mollaei@goums.ac.ir+98 17 1442 6900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026