Fracture of shaft of femur. Fracture of shaft of femur
Conditions
Interventions
Intervention 1: tranexamic acid injection
500 mg
Two Time. Intervention 2: TNG injection
5 Mic per min.
Treatment - Drugs
tranexamic acid injection
500 mg
Two Time
TNG injection
5 Mic per min
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: femoral shaft fracture; the first time; non-emergency; age 60-18 years; Normotensive being; tourniquet is not used; the amount of Hgb in the range of 12-10; following a period of 3 hours. Exclusion criteria: prohibition hypotension (eg, cardiovascular disease ); previous use of anticoagulants; unexpected factors that complicate or prolong the surgery; to be with multiple trauma; hypertensive patients; reintroduction; diseases that cause clotting disorders; including banning the use of tranexamic acid.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of bleeding. Timepoint: during anesthesia. Method of measurement: Counting blood gases, the suction,and operation field. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension. Timepoint: during anesthesia. Method of measurement: by NIBP.;Arhythmia. Timepoint: during anesthesia. Method of measurement: by monitoring of ECG.;Sever bleeding. Timepoint: during anesthesia. Method of measurement: The number of blood gas , Surgery field,suction. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Abdaviazar Sharabiani
Tehran University of Medical Sciences
Outcome results
None listed