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The effect of oral Garlic tablets(Garsin); and Fluconazole in the treatment of vaginal candidiasis

The comparison of the effect of oral Garlic tablets(Garsin); and Fluconazole in the treatment of vaginal candidiasis in women referred to Kuhdasht city health- medical centers in 1390

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201111193226N3
Enrollment
110
Registered
2012-07-16
Start date
2011-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vaginal candidiasis. Candidiasis of vulva and vagina

Interventions

Intervention 1: Intervention-3 doses 500mg meal Garsin tablet for 7 days. Intervention 2: Control- single dose 150 mg Fluconazole meal capsule.
Treatment - Drugs
Intervention-3 doses 500mg meal Garsin tablet for 7 days
Control- single dose 150 mg Fluconazole meal capsule

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 44 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women were 18-44 years old and were married; They had a single sexual partner and they themselves were the only sexual partner of their respective spouse; They had not used antibiotics, immunosuppressive drugs, or vaginal drugs 14 days before the study; They did not suffer from trichomonal vaginitis, bacterial vaginitis, or cervicitis based on direct smear, which was controlled by examining the patient's discharge; They were not at pregnancy or breast-feeding stage; They were not menopause (priority of not being menopause was higher than age criterion, i.e. They must have been non-menopause even if they were younger than 49 years old); They had not previously suffered from known medical diseases such as diabetes, immune system attenuating diseases (such as AIDS) or use of immunosuppressive drugs, auto-immune diseases, coagulation disorders, and epilepsy; They were not menstruated, and had no bleeding or breakthrough bleeding when they visited the clinics; candidiasis culture was in agreement with clinical symptoms and patient's complaints. Exclusion ceiteria: pregnancy in study time table; emergency use of antibiotic in study time and druges intulerance.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Vaginitis. Timepoint: Four to 7 days ofter completion of the treatment period. Method of measurement: Accomplished demographic information questionnaire and clinical performance checklist, clinical observation-pH value vaginal discharge and direct microscopy examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEbrahimi-Farzaneh

Clinical and treatment net

farzanehebrahimy@gmil.com+98 66 3624 0671

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026