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Protective role of Resveratrol in Heart surgery

The protective Potential of resveratrol in the prevention and reduction of complications in patients undergoing elective coronary artery bypass grafting surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20111119008129N12
Enrollment
60
Registered
2022-06-18
Start date
2022-06-20
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of the circulatory system. Ischemic heart diseases

Interventions

Intervention 1: Intervention group: To this group will be given 250 mg capsules of Resveratrol ( 98% pure, AllNatural, Nutritional INC, Winnipeg, Canada). two times a day, morning and evening for

Sponsors

Boushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Intention of the patients to participate in the trial Patients on elective surgery Having no addiction to any drugs or alcohol Not having mental or psychological disorders Participants with the age between 30 to 70 years

Exclusion criteria

Exclusion criteria: History of having chronic kidney disease, History of having chronic liver disease Having heart surgery before

Design outcomes

Primary

MeasureTime frame
The heart function. Timepoint: Around 24 hours, before the start of Resveratrol consumption, and 12 to 24 hours after the period of 60 days of consumption. Method of measurement: By echocardiography.;Diastolic blood pressure. Timepoint: Around 24 hours, before the start of Resveratrol consumption, and 12 to 24 hours after the period of 60 days of consumption. Method of measurement: By sphygmomanometer, Mercury Type ( Microlife company).;Systolic blood pressure. Timepoint: Around 24 hours, before the start of Resveratrol consumption, and 12 to 24 hours after the period of 60 days of consumption. Method of measurement: By sphygmomanometer, Mercury Type ( Microlife company).

Secondary

MeasureTime frame
Total Antioxidant Capacity( TAC). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By ELISA technique.;LDH (lactate dehydrogenase). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By reliable kits( By using spectrophotometry).;TBRS. Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By ELISA technique.;CK-MB (creatine kinase MB). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By reliable kits( By using spectrophotometry).;NO (Nitric oxide). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By ELISA technique.;TNF-a (tumor necrosis factor-a). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By ELISA technique.;Hs-CRP (High-sensitivity C-reactive Protein). Timepoint: ?Around 24 hours, before the start of Resveratrol consumption, and 24 to 72 hours after the period of 60 days of Resveratrol consumption. Method of measurement: By reliable kits( By using spectrophotometry).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Movahed

Boushehr University of Medical Sciences

a.movahed@BPUMS.ac.ir+98 77 3332 4044

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026