Comparison between cefixime and co-amoxiclave therapeutic effects in outpatient treatment of acute community acquired pneumonia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111186056N4

Enrollment

310

Registered

2011-11-21

Start date

2007-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Pneumonia due to Haemophilus influenzae

Interventions

Intervention 1: Intervention group: Cefixime 400mg/day + 2 placebo capsuls for 2 weeks. Intervention 2: Control group: Co-amoxiclave 625mg/tds for 2 weeks.

Treatment - Drugs

Intervention group: Cefixime 400mg/day + 2 placebo capsuls for 2 weeks

Control group: Co-amoxiclave 625mg/tds for 2 weeks

Eligibility

Sex/Gender

All

Age

15 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: diagnosis of acute community acquired pneumonia; age more than15 years and capable of giving informed consent. Exclusion criteria: immune deficiency disease or corticosteroids medication; allergy to beta-lactam drugs and weight less than 35 kg

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Therapeutic effects. Timepoint: At the begining, 2th and 4th weeks. Method of measurement: Clinical examination and chest X ray.	—

Secondary

Measure	Time frame
Pulmonary abscess. Timepoint: Second and 4th weeks. Method of measurement: Clinical examination and chest X ray.;Pulmonary empyema. Timepoint: 2TH,4TH WEEKS. Method of measurement: clinical examination and CXR.;Pleural effusion. Timepoint: Second and 4th weeks. Method of measurement: Clinical examination and chest X ray.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nader Zarinfar

Arak University of Medical Sciences

zarinfar@arakmu.ac.ir+98 86 1223 5605

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026